COMP Imaging Lecture Series - Lecture 4: MR Spectroscopy with Dr. Atiyah Yahya – January 24th, 1-2pm EST
Proton (1H) Magnetic Resonance Spectroscopy (MRS) enables non-invasive quantification of metabolites in tissue. The presentation will provide an overview of MRS including concepts such as chemical shift, J-coupling and MRS pulse sequences. Challenges in metabolite quantification due to overlap of peaks will be discussed. Examples of how spectral editing, where differences in J-coupling evolution of different proton spin systems can be exploited to resolve target spins of interest, will be presented. The presentation describes how timings of a Point RESolved Spectroscopy (PRESS) MRS pulse sequence can be optimized for signal from metabolite protons of interest while suppressing that from contaminating spins. Examples from research work conducted at 3 T and at 9.4 T will be provided.
Speakers / Panelists
Atiyah Yahya
Atiyah Yahya
Atiyah Yahya
Dr. Atiyah Yahya is a Medical Physicist at the Cross Cancer Institute (Edmonton, AB) and an Associate Professor in the Department of Oncology at the University of Alberta (Edmonton, AB). She has a B.Sc. in Engineering Physics from the University of Alberta (1999) and a Ph.D. in Medical Sciences-Biomedical Engineering and Electrical and Computer Engineering from the University of Alberta (2006). She is CCPM (Canadian College of Physicists in Medicine) certified in Magnetic Resonance Imaging (MRI) Physics, Diagnostic Radiological Physics and the Physics of Mammography and is a Fellow of the CCPM. Dr. Yahya's research field of expertise is magnetic resonance spectroscopy (MRS). Her research involves optimizing MRS techniques for the improved detection and quantification of metabolites relevant to cancer including lipids.